Sugimura Satoshi:Tenured Faculties|TUAT's tenure-track program

Research Support Office Research Advancement Division. Tokyo University of Agriculture and Technology

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Sugimura Satoshi

Affiliation	Institute of Agriculture
Division	Division of Biological Production
Research field	Animal Reproduction
Keyword(S)	Cattle, Oocyte, Embryo
Url	http://web.tuat.ac.jp/~fscenter/sugimura.html

Research experience	･Apr. 2008-Mar. 2009: JSPS Postdoctoral Fellow, Tohoku University ･Apr. 2009-Mar. 2012: Postdoctoral Fellow, National Livestock Breeding Center ･Apr. 2012-Oct. 2013: JSPS Postdoctral Fellow for Research Abroad, University of Adelaide ･Nov. 2013-Oct. 2018: Associate Professor, Tokyo University of Agriculture and Technology ･Nov．2018-Sep. 2022: Associate Professor, Tokyo University of Agriculture and Technology (Tenured) ･Oct. 2022-Present: Professor (Career Challenge), Tokyo University of Agriculture and Technology
Educational background	･2003, B.S., Faculty of Veterinary Medicine and Animal Science, Nippon Veterinary and Animal Science University ･2005, M.S., Graduate School of Agricultue, Tohoku University ･2008, Ph.D., Graduate School of Agriculture, Tohoku University
Awards	* The latest information is shown at the member's website. (At Nov. 2018) ･2011, Incentive Award of Japanease Society of Animal Science
Selected papers and publications	* The latest information is shown at the member's website. (At Nov. 2013) ･Sugimura S., Akai T., Hashiyada Y., Aikawa Y., Ohtake M., Matsuda, H., Kobayashi, S., Kobayashi, E., Konish, K., and Imai, K., "Effect of embryo density on in vitro development and gene expression in bovine in vitro-fertilized embryos cultured in a microwell system.", Journal of Reproduction and Development, 59, 155-122 (2013). ･Sugimura S., Matoba S., Hashiyada Y., Aikawa Y., Ohtake M., Matsuda H., Kobayashi S., Konishi K., and Imai K., "Oxidative phosphorylation-linked respiration in individual bovine oocytes.", Journal of Reproduction and Development, 58, 636-641 (2012). ･Sugimura S., Akai T., Hashiyada Y., Somfai T., Inaba Y., Hirayama M., Yamanouchi T., Matsuda H., Kobayashi S., Aikawa Y., Ohtake M., Kobayashi E., Konishi K., and Imai K., "Promising system for selecting healthy in vitro–fertilized embryos in cattle.", PLoS ONE 7, e36627 (2012). ･Sugimura S., Kobayashi S., Hashiyada Y., Ohtake M., Kaneda M., Yamanouchi T., Matsuda H., Aikawa Y., Watanabe S., Nagai T., Kobayashi E., Konishi K., and Imai K., "Follicular growth-stimulated cows provide favorable oocytes for producing cloned embryos.", Cellular Reprogramming, 14, 29-37 (2012). ･Sugimura S., Akai T., Somfai T., Hirayama M., Aikawa Y., Ohtake M., Hattori H., Kobayashi S., Hashiyada Y., Konishi K., and Imai K., "Time-lapse cinematography compatible polystyrene-based microwell culture system: a novel tool for tracking the development of individual bovine embryos.", Biology of Reproduction, 83, 970-978 (2010) ･Sugimura S., Yokoo M., Yamanaka KI., Kawahara M., Wakai T., Abe H., and Sato E., "Anomalous oxygen consumption in porcine somatic cell nuclear transfer embryos.", Cellular Reprogramming, 12, 463-474 (2010). ･Sugimura S., Yamanaka KI., Kawahara M., Wakai T., Yokoo M., and Sato E., "Early metaphase II oocytes treated with dibutyryl cAMP provide suitable recipient cytoplasm for the production of miniature pig somatic cell nuclear transfer embryos.", Animal Science Journal, 81, 48-57 (2010).

Research Description

Most of dairy cattle are derived from either artificial insemination (AI) or Embryo transfer (ET) in Japan. AI is widely used technique for producing milk and elite calves. ET allow to increase number of offspring compared with AI. ET is a technique that can greatly increase the number of calves that a genetically important. However, super cow have low reproductive activity which is shown as low pregnancy rate wit AI and hard to collect good quality embryo because of negative energy balance. Furthermore, there are various problems with decease in number of embryo collection by continuous treatment of superovulation, aging of donors and different response to superovulation in individual animals. For overcoming the problems, ovum pickup (OPU)-in vitro fertilization (IVF) has been developed. OPU-IVF is contracted by following possess; collection of cumulus-oocyte complexes from cow by OPU, in vitro maturation, in vitro fertilization, in vitro culture and ET to recipient cow. Thus, in vitro production of embryos (IVP) technique is crucial for efficient and stable production of OPU-IVF derived calves. However, IVP derived embryos have poor quality on embryo development and viability compared with in vivo produced those, and many pathologies have also been described in neonates, including abortion and large offspring. Thus, further development and improvement of IVP should determine the “efficient and stable production of dairy cows”. Hence, my topics is to produce and select viable IVP derived embryos. I believe that development and diffusion of IVP technique allow to increase profitability for dairy farmer.

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About TUAT's tenure-track program

I believe that setting new lab from “zero” is the big chance for establishing identity as a researcher. I am thinking that groundwork to survive as a researcher is important as well as increasing number of the paper required for tenure. This system is considered environmentally so draw the future vision on research and education after getting the tenure.

Future aspirations

Agricultural science and animal science are quite dynamic studies. I aim education and research which are conscious of commercialization and diffusion of technology as well as basic and applied sciences, which can be fed back to the site. In addition, I will continue to challenge the education and research that combines nutrition, management and reproduction, which is taking advance of FS center.