Muraoka Takahiro:Tenured Faculties|TUAT's tenure-track program

Research Support Office Research Advancement Division. Tokyo University of Agriculture and Technology

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This program is supported by MEXT’s scientific technology human resource development fee grant, "Program to Disseminate Tenure Tracking System".

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Muraoka Takahiro

Affiliation	Institute of Engineering
Division	Division of Applied Chemistry
Research field	Bio-related Chemistry, Supramolecular Chemistry, Organic Chemistry
Keyword(S)	Self-assembly, Lipid Bilayer, Peptides, Stimuli-responsive Molecules, Molecular Machines
Url	https://www.muraoka-lab.com/

Research experience	･Apr.2004–Mar.2007：JSPS Young Scientists Fellowship ･Jul.2006–Apr.2008：Visiting Scholar, Northwestern University ･Apr.2007–Apr.2008：JSPS Research Fellowship for Young Scientists ･May.2008–Apr.2015：Assistant Professor, Tohoku University ･Oct.2013–Present：JST PRESTO Researcher ･May.2015–Jan.2017：Assistant Professor, Tokyo Institute of Technology ･Feb.2017-Mar.2020: Associate professor, Tokyo University of Agriculture and Technology ･Apr.2020-Nov.2020: Associate Professor(Tenured), Tokyo University of Agriculture and Technology ･Dec.2020-Present: Professor(Career Challenge), Tokyo University of Agriculture and Technology
Educational background	・Mar.2002：B.Eng., Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo ・Mar.2004：M.Eng., Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo ・Mar.2007：Ph.D., Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo
Awards	* The latest information is shown at the member's website. (At Apr. 2020) ・2007：Dean’s Prize (Graduate School of Engineering, The University of Tokyo) ・2009：Inoue Research Award for Young Scientists (Inoue Research Foundation) ・2014：CSJ Presentation Award (Chemical Society of Japan) ・2015：CSJ Award for Young Chemists (Chemical Society of Japan) ・2016：The Young Scientists’ Prize in The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology (MEXT) ・2018：Tokyo University of Agriculture and Technology, President's Award
Selected papers and publications	* The latest information is shown at the member's website. (At Apr. 2020) ・T. Muraoka, K. Kinbara, T. Aida, Nature, 440, 512 (2006). ・T. Muraoka, H. Cui, S. I. Stupp, J. Am. Chem. Soc., 130, 2946 (2008). ・T. Muraoka, C.-Y. Koh, H. Cui, S. I. Stupp, Angew. Chem. Int. Ed., 48, 5946 (2009). ・T. Muraoka, T. Shima, T. Hamada, M. Morita, M. Takagi, K. V. Tabata, H. Noji, K. Kinbara, J. Am. Chem. Soc., 134, 19788 (2012). ・T. Muraoka, K. Adachi, M. Ui, S. Kawasaki, N. Sadhukhan, H. Obara, H. Tochio, M. Shirakawa, K. Kinbara, Angew. Chem. Int. Ed., 52, 2430 (2013). ・T. Shima, T. Muraoka, N. Hoshino, T. Akutagawa, Y. Kobayashi, K. Kinbara, Angew. Chem. Int. Ed., 53, 7173 (2014). ・T. Muraoka, T. Endo, K. V. Tabata, H. Noji, S. Nagatoishi, K. Tsumoto, R. Li, K. Kinbara, J. Am. Chem. Soc., 136, 15584 (2014). ・S. Okada, M. Matsusaki, K. Arai, Y. Hidaka, K. Inaba, M. Okumura, T. Muraoka, Chem. Commun., 55, 759 (2019). ・R. Miyake, A. Ando, M. Ueno, T. Muraoka, J. Am. Chem. Soc., 141, 8675 (2019). ・A. Ishida, G. Watanabe, M. Oshikawa, I. Ajioka, T. Muraoka, Chem. Eur. J., 25, 13523 (2019).

Research Description

I have studied bio-related chemistry inspired by (1) mimickry, (2) use, and (3) manipulation of biomolecules and cells. In (1) mimickry of biomolecules, synthetic molecular machines and supramolecular ion channels have been developed. In (2) use of biomolecules, photoresponsive hydrogels were constructed using self-assembling peptides. Using these photoresponsive hydrogels, photo-control of cell adhesion was successfully demonstrated, which relates to the concept (3). Additionally, in (3) manipulation of biomolecules, novel protein stabilizing molecules for aggregation suppression have been developed. I am carrying forward these concepts to develop new functional molecules in the field between chemistry and biology.

About TUAT's tenure-track program

One of the merits of the TUAT Tenure Track Program is the availability of sufficient space for research from the beginning, so that it is possible to develop the research equipments systematically. Administrative support is also helpful to focus on research and education. In this program, there are many young researchers with different backgrands, which makes this program attractive by providing many opportunities to expand our research by collaboration.

Future aspirations

I am making efforts for research and education to develop original chemistry by pursuing the new possibilities and functions of molecules with a long-term viewpoint. On the basis of synthetic and supramolecular chemistry, I am trying to develop unexplored frontier by integrating multidisciplinary areas such as biology, physics and materials science. Through such a challenging research, I lead students to their non-linear growth as researchers.