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Home > Introduction of our tenure-track faculties > Miyamoto Junki

Introduction of our tenure-track faculties

Miyamoto Junki

Affiliation Organization for Promotion of Tenure-track System / Institute of Agriculture
Division Division of Applied Biological Science
Research field Food chemistry, Gut microbiology
Keyword(S) Functional food, gut microbiota, homeostasis
Url
Research experience

・2014.04-2017.03: JSPS researcher (DC1)
・2017.04-2020.09: Assistant professor, Graduate school of Agriculture, Tokyo University of Agriculture and Technology
・2020.10-present: Associate professor, Graduate school of Agriculture, Tokyo University of Agriculture and Technology

Educational background

・2010.03: Associate degree of Engineering at National Institute of Technology, Numazu College
・2012.03: Bachelor of Agriculture at Hiroshima University
・2014.03: Master of Agriculture at Hiroshima University
・2017.03: Ph.D. (Agriculture) at Hiroshima University

Awards

・2019: JES, Young Investigator Award
・2020: Young Investigator Okamoto Award
・2020: Japan Prize in Agricultural Sciences, Achievement Award for Young Scientists

Selected papers and publications

・Kimura I#, Miyamoto J#, Ohue-Kitano R, Watanabe K, Yamada T, Onuki M, Aoki R, Isobe Y, Kashihara D, Inoue D, Inaba A, Takamura Y, Taira S, Kumaki S, Watanabe M, Ito M, Nakagawa F, Irie J, Kakuta H, Shinohara M, Iwatsuki K, Tsujimoto G, Ohno H, Arita M, Itoh H, Hase K. Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice. Science. 2020. 367: eaaw8429. #Contribution equally 1st author
・Miyamoto J, Ohue-Kitano R, Mukouyama H, Nishida A, Watanabe K, Igarashi M, Irie J, Tsujimoto G, Satoh-Asahara N, Itoh H, Kimura I. Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions. Proc Natl Acad Sci U S A. 2019. 116: 23813-23821.
・Miyamoto J, Igarashi M, Watanabe K, Karaki SI, Mukouyama H, Kishino S, Li X, Ichimura A, Irie J, Sugimoto Y, Mizutani T, Sugawara T, Miki T, Ogawa J, Drucker DJ, Arita M, Itoh H, Kimura I. Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids. Nat Commun. 2019. 10: 4007.
・Miyamoto J, Watanabe K, Taira S, Kasubuchi M, Li X, Irie J, Itoh H, Kimura I. Barley β-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice. PLoS One. 2018. 13: e0196579.
・Miyamoto J, Mizukure T, Park SB, Kishino S, Kimura I, Hirano K, Bergamo P, Rossi M, Suzuki T, Arita M, Ogawa J, Tanabe S. A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway. J Biol Chem. 2015. 290: 2902-2918.

Research Description

It has been revealed that the diet is not only energy source, but also a variety of biological functions. In particular, the intestinal tract is a very interesting organ which is called “inner but outside world”. In addition, gut microbiota coexist in the host intestinal tract, and recent studies have suggested that the composition of gut microbiota is closely related to our health. It is well-known that the diet affect the composition of gut microbiota, and as a result, gut microbial metabolites derived from diet are expected to act the intestinal tract and peripheral organs via the blood. In our laboratory, in order to clarify the novel functional foods, we will focus on the investigation of interaction between diet and gut microbiota for our health.

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About TUAT's tenure-track program

TUAT tenure track program provides the enough time, environment, and start-up budget for our research. In addition, the educational duty is reduced during the program. We are able to receive the supports and advices on research and education from mentors and other professors. This program is a great chance for young researchers as principal investigator.

Future aspirations

I really appreciate the people who have supported for being able to establish my laboratory. During 5 years (tenure track period), I would like to contribute to the development of research even a little.